Ross Feldman, Medical Director, Cardiac Sciences Program


Volume 3, Issue 1 - January 7, 2019

Publications by our Faculty this week

Sharma R, Hiebert B, Cheung D, Jassal DS, Minhas K. Primary Coronary Intervention in Octogenarians and Nonagenarians With ST-Segment Elevation Myocardial Infarction: A Canadian Single-Center Perspective. Angiology. 2018 Sep;69(8):718-723. doi: 10.1177/0003319717746520. Epub 2017 Dec 12.

Shah AH, Ravandi A, Kass M. Platypnea-Orthodeoxia Syndrome: Reminder of the In Utero Vena Cava Flow Pattern. JACC Cardiovasc Interv. 2018 Dec 21. pii: S1936-8798(18)32206-4. doi: 10.1016/j.jcin.2018.10.040. [Epub ahead of print] No abstract available.

Dufresne J, Bowden P, Thavarajah T, Florentinus-Mefailoski A, Chen ZZ, Tucholska M, Norzin T, Ho MT, Phan M, Mohamed N, Ravandi A, Stanton E, Slutsky AS, Dos Santos CC, Romaschin A, Marshall JC, Addison C, Malone S, Heyland D, Scheltens P, Killestein J, Teunissen CE, Diamandis EP, Michael Siu KW, Marshall JG. The plasma peptides of ovarian cancer. Clin Proteomics. 2018 Dec 21;15:41. doi: 10.1186/s12014-018-9215-z. eCollection 2018.

Volume 2, Issue 51 - December 30, 2018

This Week

Restructuring the R&D Spend of CSP- Part 2.

Clinical research infrastructure/personnel support was identified as a priority in the 2018 CSP Scholarship Task Force Report. The history of that support goes back to the early days of CSP and was mostly built around CHaRM. This initiative was clearly successful in supporting a group of CSP faculty to build and maintain a research program that furthered the mandate of the Program. In this fiscal year we are tracking towards a $125-150K CSP spend on research support through CHaRM- primarily for the support of our team of research nurse,research associate and biostatistician. However, the business model upon which CHaRM was built is no longer sustainable in our current economic environment.

In 2019 we will be restructuring that support program to try to make it more accessible to more members of the CSP and to try to better align it with the needs of the CSP. The order of priority for support will be: 1) investigator-initiated, CSP faculty-led research 2) collaborative investigator-initiated research (e.g., where a CSP faculty member is a site-investigator for a CIHR multi-site study) and 3) industry research. In all cases, support will be based on a cost-sharing arrangement/partnership where the higher the priority, the greater will be the % of the total HR cost carried by the CSP.

The process for accessing these funds has yet to be established but would involve establishing mechanisms for:

i) application for support, ii) adjudication of the requests iii) allocation of in-kind support for accessing research staff time, iv) tracking of time/effort of research staff in support of individual projects and v) demonstration of productivity by CSP recipients of that support.

We would hope to roll out a draft model for this support program in Q1 2019 and look forward to your comments and suggestions.

Publications by our Faculty this week

Abdel-Wahab M, Simonato M, Latib A, Goleski PJ, Allali A, Kaur J, Azadani AN, Horlick E, Testa L, Orvin K, Kornowski R, Kass M, Don CW, Richardt G, Webb JG, Dvir D. Clinical Valve Thrombosis After Transcatheter Aortic Valve-in-Valve Implantation. Circ Cardiovasc Interv. 2018 Nov;11(11):e006730. doi: 10.1161/CIRCINTERVENTIONS.118.006730.

Kimber DE, Kehler DS, Lytwyn J, Boreskie KF, Jung P, Alexander B, Hiebert BM, Dubiel C, Hamm NC, Stammers AN, Clarke M, Fraser C, Pedreira B, Tangri N, Hay JL, Arora RC, Duhamel TA. Pre-Operative Frailty Status Is Associated with Cardiac Rehabilitation Completion: A Retrospective Cohort Study. J Clin Med. 2018 Dec 17;7(12). pii: E560. doi: 10.3390/jcm7120560.

Zeglinski MR, Moghadam AR, Ande SR, Sheikholeslami K, Mokarram P, Sepehri Z, Rokni H, Mohtaram NK, Poorebrahim M, Masoom A, Toback M, Sareen N, Saravanan S, Jassal DS, Hashemi M, Marzban H, Schaafsma D, Singal P, Wigle JT, Czubryt MP, Akbari M, Dixon IMC, Ghavami S, Gordon JW, Dhingra S. Myocardial Cell Signaling During the Transition to Heart Failure: Cellular Signaling and Therapeutic Approaches. Compr Physiol. 2018 Dec 13;9(1):75-125. doi: 10.1002/cphy.c170053.

Konigstein M, Ben-Yehuda O, Smits PC, Love MP, Banai S, Perlman GY, Golomb M, Ozan MO, Liu M, Leon MB, Stone GW, Kandzari DE. Outcomes Among Diabetic Patients Undergoing Percutaneous Coronary Intervention With Contemporary Drug-Eluting Stents: Analysis From the BIONICS Randomized Trial. JACC Cardiovasc Interv. 2018 Dec 24;11(24):2467-2476. doi: 10.1016/j.jcin.2018.09.033.

Lieben Louis X, Raj P, Chan L, Zieroth S, Netticadan T, Wigle JT. Are the cardioprotective effects of the phytoestrogen resveratrol sex dependent? Can J Physiol Pharmacol. 2018 Dec 21. doi: 10.1139/cjpp-2018-0544. [Epub ahead of print]


Volume 2, Issue 50 - December 23, 2018

This Week

Wishing everyone a very Merry Christmas/Happy Holidays! Enjoy time with your family and friends this holiday season. There are no faculty publications this week.

Volume 2, Issue 49 - December 16, 2018

This Week

Congratulations to Dr. Ashish Shah and Dr. Michael Yamashita on their successful applications to the 2018 Competition of the Manitoba Medical Service Foundation. Dr. Ashish Shah – Assistant Professor in the Department of Internal Medicine at the University of Manitoba was awarded $30,000 for their project titled ‘Novel Methods for Selecting Appropriate Patients Undergoing Trans-Catheter Aortic Valve Implantation (TAVI): A Pilot Project’ Dr. Michael Yamashita – Assistant Professor in the Department of Surgery at the University of Manitoba was awarded $25,000 for their project titled ‘Characterizing Thoracic Aortic Disease in Manitoba: Prevalence and Follow-up’

Publications by our Faculty this week

Arcinas LA, Yan W, Jassal DS, Love MP, Yamashita MH, Elbarouni B. Multimodality Imaging of a Giant Right Coronary Artery Aneurysm. Can J Cardiol. 2018 Dec;34(12):1688.e5-1688.e7. doi: 10.1016/j.cjca.2018.08.031. Epub 2018 Aug 24.

Grocott HP. Cerebral oximetry monitoring. To guide physiology, avert catastrophe or both? Eur J Anaesthesiol. 2019 Jan;36(1):82-83. doi: 10.1097/EJA.0000000000000894. No abstract available.

Graham C, Thorleifson M, Stefura WP, Funk DJ, HayGlass KT. Class II obese and healthy pregnant controls exhibit indistinguishable pro- and anti-inflammatory immune responses to Caesarian section. Immun Inflamm Dis. 2017 Sep;5(3):364-372. doi: 10.1002/iid3.174. Epub 2017 May 25.

Dufresne J, Bowden P, Thavarajah T, Florentinus-Mefailoski A, Chen ZZ, Tucholska M, Norzin T, Ho MT, Phan M, Mohamed N, Ravandi A, Stanton E, Slutsky AS, Dos Santos CC, Romaschin A, Marshall JC, Addison C, Malone S, Heyland D, Scheltens P, Killestein J, Teunissen C, Diamandis EP, Siu KWM, Marshall JG. The plasma peptidome. Clin Proteomics. 2018 Dec 1;15:39. doi: 10.1186/s12014-018-9211-3. eCollection 2018.

Magsino K, Sanjanwala R, Hiebert B, Rothney J, Manji R, Arora R, Shah P. Treatment Outcomes for Right-Sided Endocarditis in Intravenous Drug Users: A Systematic Review and Analysis of Outcomes in a Tertiary Centre. Thorac Cardiovasc Surg. 2018 Oct;66(7):552-562. doi: 10.1055/s-0037-1618578. Epub 2018 Jan 19. Review.

Martin A, Yamashita MH. Bioprosthetic aortic valve replacement: A high standard of comparison for transcatheter aortic valve implantation. J Thorac Cardiovasc Surg. 2018 Nov 8. pii: S0022-5223(18)32910-6. doi: 10.1016/j.jtcvs.2018.10.131. [Epub ahead of print] No abstract available.

Volume 2, Issue 48 - December 8, 2018

This Week

Dr. Colette Seifer has been appointed as Associate Director of the Cardiac Sciences Program effective December 1. With the progression of restructuring that we are undergoing both at the regional and provincial level there are an increasing number of occasions when I need to be in two places at once. Colette has agreed to help me avoid those circumstances :-). Beyond that, she will be my designate on those occasions when I am out of town-- like this week while I try to avoid damaging myself on the ski hills of Colorado. Thanks Colette for stepping up!

CSP News

Dr. Carly Lodewycks was highlighted in this month's newsletter from the Rady Faculty of Medicine featuring rising stars in clinical research. Congrats Carly!

Publications by our Faculty this week

Chatterjee S, Shake JG, Arora RC, Engelman DT, Firstenberg MS, Geller CM, Hirose H, Lonchyna VA, Lytle FT, Milewski RKC, Moosdorf RGH, Rabin J, Sanjanwala R, Galati M, Whitman GJ; Society of Thoracic Surgeons Workforce on Critical Care. Handoffs from the Operating Room to the Intensive Care Unit after Cardiothoracic Surgery: From the Society of Thoracic Surgeons Workforce on Critical Care. Thoracic Surgeons Workforce on Critical Care. Ann Thorac Surg. 2018 Nov 27. pii: S0003-4975(18)31704-1. doi: 10.1016/j.athoracsur.2018.11.010. [Epub ahead of print] No abstract available.

Volume 2, Issue 47 - December 1, 2018

This Week

A word on professionalism

The CSP recognizes that our fundamental mission is the care of our patients. Maintaining a safe and respectful workplace is a necessary condition for fulfilling this mission. The (pen)ultimate responsibility for ensuring this may fall to the leadership of the CSP. However, it is only by each member of the community maintaining a high standard of professionalism can we achieve and maintain a safe and respectful workplace. It is expected that we will all experience lapses in professionalism; the true measure of our professionalism is not in absolute avoidance of such situations, but in how we handle them, when they do arise. This week we saw several lapses in that high standard. There are institutional mechanisms for reporting lapses. We have encouraged the use of the RL6 system for reporting incidents where you feel intimidated or disrespected. Trainees in the program need to remember that there are additional Rady Faculty of Medicine mechanisms (the Speakup Program). However, beyond those formal processes it is particularly important for each of us to redouble our commitment to maintaining a respectful workplace. At times we have significant and important differences in our opinions relating to patient care- either on an individual case basis or on overall organization of care systems. However, we have to always remember that notwithstanding the depths of these differences, are interdependence as health care professionals means that we need to reconcile these differences safely and respectfully in order to do our jobs effectively.

Publications by our Faculty this week

Devereaux PJ, Duceppe E, Guyatt G, Tandon V, Rodseth R, Biccard BM, Xavier D, Szczeklik W, Meyhoff CS, Vincent J, Franzosi MG, Srinathan SK, Erb J, Magloire P, Neary J, Rao M, Rahate PV, Chaudhry NK, Mayosi B, de Nadal M, Iglesias PP, Berwanger O, Villar JC, Botto F, Eikelboom JW, Sessler DI, Kearon C, Pettit S, Sharma M, Connolly SJ, Bangdiwala SI, Rao-Melacini P, Hoeft A, Yusuf S; MANAGE Investigators. Dabigatran in patients with myocardial injury after non-cardiac surgery (MANAGE): an international, randomised, placebo-controlled trial. Lancet. 2018 Jun 9;391(10137):2325-2334. doi: 10.1016/S0140-6736(18)30832-8. Erratum in: Lancet. 2018 Jul 7;392(10141):30.

Arcinas LA, Liu S, Schacter GI, Kass M. Cerebral Air Embolism Following Central Venous Catheter Removal. Am J Med. 2017 Dec;130(12):e549-e550. doi: 10.1016/j.amjmed.2017.07.024. Epub 2017 Aug 10. No abstract available.


Volume 2, Issue 46 - November 25, 2018

This Week

CSP Pilot Project-Fall Grants Competition. As enunciated in the Report of the CSP Task Force for Scholarship, one of the goals of the CSP R&D investment is to provide greater support for innovative projects which represent collaborative efforts across the 3 sections of the Program and the ICS. Additionally, given the limited funds available for R&D/scholarship we will aim to provide support for projects which have the potential for further expansion into more extensive research/scholarship programs. Thus, in adjudicating the ten applications submitted for this inaugural pilot project competition, the review panel were tasked to prioritize them based on their assessment of 1) innovation, 2) collaboration, 3) feasibility (including assessment of the track record of the PI) and 4) potential for funding to be leveraged into a larger research program (i.e., potential for subsequent peer-review funding). Based on these criteria 2 projects were awarded funding in this fall's competition, viz.

Amir Ravandi “Predictors of post myocardial infarction adverse events through continuous biometric data, machine learning, and artificial intelligence (PRECISION Study)”

Rizwan Manji “Does aortic stenosis have an autoimmune component?”

We look forward to following the progress of these 2 projects. Further, we will be considering what we learned through this process in implementing the next pilot project competition, slated for Q2 2019.

Shout Outs

Congrats to our IM Resident Research Day Awardees!
Liane Arcinas, PGY3 – Internal Medicine 1st prize, Clinical Investigation Podium Presentation by a Core Resident “NURSE PRACTITIONER TRANSITION CLINIC OUTCOMES: COMPARATIVE ANALYSIS OFTRADITIONAL VS. EXPEDITED POST HOSPITAL DISCHARGE FOLLOW-UP.” SUPERVISOR: Shelley Zieroth
Evan Wiens PGY2 Internal Medicine - Emy Ozamota Award SIGNAGE AS AN INTERVENTION ON A GENERAL MEDICINE WARD TO REDUCE UNNECESSARY TESTING: RESULTS OF THE SIGN-RUN STUDY SUPERVISOR: Colette Seifer

Publications by our Faculty this week

Stamenkovic A, Pierce GN, Ravandi A.
Oxidized Lipids: Not just another brick in the wall. Can J Physiol Pharmacol. 2018 Nov 16. doi: 10.1139/cjpp-2018-0490. [Epub ahead of print]

Nhola LF, Abdelmoneim SS, Villarraga HR, Kohli M, Grothey A, Bordun KA, Cheung M, Best R, Cheung D, Huang R, Barros-Gomes S, Pitz M, Singal PK, Jassal DS, Mulvagh SL. Echocardiographic Assessment for the Detection of Cardiotoxicity Due to Vascular Endothelial Growth Factor Inhibitor Therapy in Metastatic Renal Cell and Colorectal Cancers. J Am Soc Echocardiogr. 2018 Nov 17. pii: S0894-7317(18)30537-6. doi: 10.1016/j.echo.2018.09.019. [Epub ahead of print]

Costa EC, Hay JL, Kehler DS, Boreskie KF, Arora RC, Umpierre D, Szwajcer A, Duhamel TA. Effects of High-Intensity Interval Training Versus Moderate-Intensity Continuous Training On Blood Pressure in Adults with Pre- to Established Hypertension: A Systematic Review and Meta-Analysis of Randomized Trials. Sports Med. 2018 Sep;48(9):2127-2142. doi: 10.1007/s40279-018-0944-y. Review.

Asgar AW, Lauck S, Ko D, Lambert LJ, Kass M, Adams C, Nadeem N, Oakes GH, Alqoofi F, Webb JG; CCS Quality Indicators TAVI Working Group. The Transcatheter Aortic Valve Implantation (TAVI) Quality Report: A Call to Arms for Improving Quality in Canada. Can J Cardiol. 2018 Mar;34(3):330-332. doi: 10.1016/j.cjca.2017.11.007. Epub 2017 Nov 22.


Volume 2, Issue 45 - November 18, 2018

This Week

Please join us this Wednesday November 21, 2018 at 4:00 PM in the Sam Cohen Auditorium, Albrechtsen Research Centre for the Cardiac Sciences Program’s monthly Visiting Professor Series Lecture. Dr. Sean Connors, Medical Director Cardiac Sciences Program Eastern Health/MUN will be our second guest of the season. Join us at 4PM for his talk “Newfoundland curse”: development of a new paradigm for mutation-based management of heart disease followed by a reception in the Atrium from 5-6 PM. Hope to see you there!

Shout Outs

Congratulations to Carly Lodewyks for waving the flag of the CSP at her poster at last week's AHA in Chicago!

Congratulations to Dr Christopher Parr as gold medal recipient for best clinical research oral presentation at this year's Dhalla ICS Research Day!

Publications by our Faculty this week

Yan W, Arora RC, Yamashita MH. Does valve choice matter in patients receiving hemodialysis? J Thorac Cardiovasc Surg. 2018 Oct 6. pii: S0022-5223(18)32559-5. doi: 10.1016/j.jtcvs.2018.09.055. [Epub ahead of print] No abstract available.

Sequiera GL, Sareen N, Sharma V, Surendran A, Abu-El-Rub E, Ravandi A, Dhingra S. High Throughput screening reveals no significant changes in protein synthesis, processing and degradation machinery during passaging of mesenchymal stem cells. Can J Physiol Pharmacol. 2018 Nov 13. doi: 10.1139/cjpp-2018-0553. [Epub ahead of print]

Grocott HP. Lung isolation for emergent thoracotomy in the bleeding airway patient: the choice of bronchial blocker may make a difference. Rev Bras Anestesiol. 2018 Nov 5. pii: S0034-7094(18)30333-7. doi: 10.1016/j.bjan.2018.07.005. [Epub ahead of print] Portuguese. No abstract available.


Volume 2, Issue 44 - November 11, 2018

TCA/PA Reorg Task Force. PA/CA reorganization.

In the course of meeting with all of the physicians assistants and clinical assistants in conjunction with their annual Performance Conversations I have been impressed by the extent the program has grown from the first "pioneer" CAs in the Cardiac Surgery wards in the late 1980's to our present complement slated to increase to up to 18- with the implementation of the Phase 2 Consolidation Plan. CA/PAs are critical to many clinical aspects of the CSP and their roles are expected to further expand over the next several years. It is in this context that I have constituted a task force to examine the current basis for distribution/assignments of CA/PAs, to set priorities for coverage of the range of our clinical activities and to set minimum expectations and limits for clinical loads. Representatives from Cardiology , Cardiac Surgery and the CSP CA/PAs have been recruited for this important task. Their report, expected by Q2 2019, will be shared and discussed with the program.

Milestones

Karlene Luchka will be leaving us this week to take on a new PA position in general surgery at Bethesda Hospital in Steinbach. We wish her the best in her new position.

Publications by our Faculty this week

Grocott HP. Burnout: Yes, it's a health problem, but is the solution partly linked to professionalism? J Clin Anesth. 2018 Mar;45:1. doi: 10.1016/j.jclinane.2017.11.033. Epub 2017 Dec 5. No abstract available.


Volume 2, Issue 43 - November 3, 2018

Defining Fund Raising Priorities for 2019
The SBH Foundation remains a very important source of support for new CSP initiatives and is the basis for ongoing CSP programs including CHaRM, the recent pilot projects and the technology/equipment support competitions. Over the past year I have based my discussions with the Foundation on the white paper we developed in October 2017 with input from all sections on fundraising priorities. It is time to revisit those priorities starting from scratch. Please think about those smaller (less than $100 K), medium ($100 - 500 K), larger ($0.5 M - 5.0 M) and jumbo (greater than $5 M) projects that you would like to see supported over the next 5 years. Rakesh, Colette and Scott will be asked to submit priority lists from their respective sections. Stay tuned.

Shout Outs

Welcome to Kiran Singh, the program's new Administrative Director!

Publications by our Faculty this week

Mazer CD, Whitlock RP, Fergusson DA, Belley-Cote E, Connolly K, Khanykin B, Gregory AJ, de Médicis É, Carrier FM, McGuinness S, Young PJ, Byrne K, Villar JC, Royse A, Grocott HP, Seeberger MD, Mehta C, Lellouche F, Hare GMT, Painter TW, Fremes S, Syed S, Bagshaw SM, Hwang NC, Royse C, Hall J, Dai D, Mistry N, Thorpe K, Verma S, Jüni P, Shehata N; TRICS Investigators and Perioperative Anesthesia Clinical Trials Group. Six-Month Outcomes after Restrictive or Liberal Transfusion for Cardiac Surgery. N Engl J Med. 2018 Sep 27;379(13):1224-1233. doi: 10.1056/NEJMoa1808561. Epub 2018 Aug 26.


Volume 2, Issue 42 - October 28, 2018


Shout Outs
Big shout out to Shelley Zieroth who was just elected as President of the Canadian Heart Failure Society and to the Council of the Canadian Cardiovascular Society Council at this year's Canadian Cardiovascular Congress.

Publications by our Faculty this week

Kehler DS, Hay JL, Stammers AN, Hamm NC, Kimber DE, Schultz ASH, Szwajcer A, Arora RC, Tangri N, Duhamel TA. A systematic review of the association between sedentary behaviors with frailty. Exp Gerontol. 2018 Oct 22;114:1-12. doi: 10.1016/j.exger.2018.10.010. [Epub ahead of print] Review.

Spence J, Belley-Côté E, Oczkowski S, Jacobsohn E, Whitlock R, Devereaux PJ, Connolly S. When and how should we cluster and cross over: methodological and ethical issues (letter 1). Can J Anaesth. 2018 Oct 17. doi: 10.1007/s12630-018-1237-5. [Epub ahead of print] No abstract available.

Agarwal P, Cole LK, Chandrakumar A, Hauff KD, Ravandi A, Dolinsky VW, Hatch GM. Phosphokinome Analysis of Barth Syndrome Lymphoblasts Identify Novel Targets in the Pathophysiology of the Disease. Int J Mol Sci. 2018 Jul 12;19(7). pii: E2026. doi: 10.3390/ijms19072026.

Shehata N, Whitlock R, Fergusson DA, Thorpe KE, MacAdams C, Grocott HP, Rubens F, Fremes S, Lellouche F, Bagshaw S, Royse A, Rosseel PM, Hare G, Medicis E, Hudson C, Belley-Cote E, Bainbridge D, Kent B, Shaw A, Byrne K, Syed S, Royse CF, McGuiness S, Hall J, Mazer CD. Transfusion Requirements in Cardiac Surgery III (TRICS III): Study Design of a Randomized Controlled Trial. J Cardiothorac Vasc Anesth. 2018 Feb;32(1):121-129. doi: 10.1053/j.jvca.2017.10.036. Epub 2017 Nov 3.

Volume 2, Issue 41 - October 21, 2018


In The News

This will be a busy week for the CSP- beyond many of you catching up after your return from the CCC in Toronto. The second Visiting Professor seminar for the year is being held Wednesday at 4 pm. Dr. Manos Brilakis, University of Minnesota, will be talking about “Contemporary Treatment of Coronary Chronic Total Occlusions. Look forward to seeing you there. Additionally, the first provincial workshop for Shared Health's Cardiothoracic and Vascular provincial clinical team will be held Friday. I co-chair the team which includes the CSP leadership. We will report on the progress of this important initiative.

Annual Reviews. On my arrival in Winnipeg my initial plan was to formally meet with all physicians annually to review our progress. I will be continue that plan for all physician assistants/clinical assistants. However, for faculty members of the Cardiology, Cardiac Surgery and Cardiac Anaesthesia sections, I will be deferring to the annual evaluations by your section chiefs which I will review with them. On the other hand, I am more than happy to schedule an annual performance conversation (including coffee :-)) with any/all CSP physicians at their request. Let me/Janessa know.

Shout Outs
Congratulations to Dr. Michael Yamashita, his wife Meme on the birth of their new baby boy Daniel.
Congratulations to Carly Lodewyks for receiving her MSc from the Department of Community Health Sciences!


Publications by our Faculty this Week

Grocott HP, Bryson GL. By any other name: consensus in the nomenclature of perioperative neurocognitive disorders. Can J Anaesth. 2018 Nov;65(11):1171-1174. doi: 10.1007/s12630-018-1215-y. Epub 2018 Oct 16. No abstract available.

Grocott HP. Letter by Grocott Regarding Article, "Evolution of Cognitive Function After Transcatheter Aortic Valve Implantation". Circ Cardiovasc Interv. 2017 Feb;10(2):e004829. doi: 10.1161/CIRCINTERVENTIONS.116.004829. No abstract available.

Volume 2, Issue 40 - October 14, 2018


Publications by our Faculty this Week

Grocott HP. Anesthetic Agents and Postoperative Delirium after Off-pump Coronary Bypass Graft Surgery: An Insufficiently Complex Approach to a Complex Problem. J Cardiothorac Vasc Anesth. 2018 Aug;32(4):e87-e88. doi: 10.1053/j.jvca.2018.03.024. Epub 2018 Mar 21. No abstract available.

Grocott HP. Optimizing Lung Collapse With a Bronchial Blocker: It's Not What You Use, but How You Use It. J Cardiothorac Vasc Anesth. 2018 Aug;32(4):e93-e94. doi: 10.1053/j.jvca.2018.03.006. Epub 2018 Mar 7. No abstract available.

Alex S, Hiebert B, Arora R, Menkis A, Shah P. Survival and Long-Term Outcomes of Aortic Valve Replacement in Patients Aged 55 to 65 Years. Thorac Cardiovasc Surg. 2018 Jun;66(4):313-321. doi: 10.1055/s-0037-1602825. Epub 2017 May 16.


Volume 2, Issue 39 - October 7, 2018

CSP News of the Week

Remember the date. CSP Faculty Meeting October 17, 5 pm. Let me know if there are any agenda items you would like to see added.

Publications by our Faculty this Week

Yanagawa B, Graham MM, Afilalo J, Hassan A, Arora RC. Frailty as a risk predictor in cardiac surgery: Beyond the eyeball test. J Thorac Cardiovasc Surg. 2018 Sep 5. pii: S0022-5223(18)32301-8. doi: 10.1016/j.jtcvs.2018.08.054. [Epub ahead of print] No abstract available.

Schultz A, Dahl L, McGibbon E, Brownlie J, Cook C, Elbarouni B, Katz A, Nguyen T, Sawatzky JA, Sinclaire M, Throndson K, Fransoo R. Health Outcome and Follow-up Care Differences Between First Nation and Non-First Nation Coronary Angiogram Patients: A Retrospective Cohort Study. Can J Cardiol. 2018 Oct;34(10):1333-1340. doi: 10.1016/j.cjca.2018.07.418. Epub 2018 Jul 29.

Grocott HP. Nuances of the cervical interfascial plane and multifidus cervicis plane blocks: Balancing efficacy and risk as a function of technique. J Clin Anesth. 2018 Feb;44:82-83. doi: 10.1016/j.jclinane.2017.10.013. No abstract available.

Volume 2, Issue 38 - September 29, 2018

CSP News of the Week

The CSP welcomes our new members to the team as our complement of CA/PAs continue to grow!
Dana Baker is a new graduate of the MPAS Program.
Jamie Chalmers is a new graduate from the MPAS Program.
Sara Doak is a new graduate from the MPAS program.
Dr. Zengxuan Hu was trained in Urology in China and in General Surgery at UBC.
Dr. Dorsaf Gaied, Dorsaf is a Cardiac surgeon from Tunisia, previously trained in Tunisia and Europe (Monaco+Belgium) Fellowships in cardiac surgery in Quebec (IUCPQ) and in Halifax.


Shout Outs

Last weekend the CSP ran our first official CSU-ALS team course. We are the first centre in Canada to undergo this type of training for our CVICU staff. A special thank you for Belinda Landry for all her organization and to the rest of the team involved: Dr. Rakesh Arora, Reid Love, Sandy Warren, Kim Kummen, Crystal Gurney and Aaron and Josh from CSIU-ALS North America. Congrats!


Publications by our Faculty this Week

Giambruno V, Chu MW, Fox S, Swinamer SA, Rayman R, Markova Z, Barnfield R, Cooper M, Boyd DW, Menkis A, Kiaii B. Robotic-assisted coronary artery bypass surgery: an 18-year single-centre experience. Int J Med Robot. 2018 Jun;14(3):e1891. doi: 10.1002/rcs.1891. Epub 2018 Jan 19.

Villafranca A, Fast I, Jacobsohn E. Disruptive behavior in the operating room: prevalence, consequences, prevention, and management. Curr Opin Anaesthesiol. 2018 Jun;31(3):366-374. doi: 10.1097/ACO.0000000000000592. Review.

Grocott HP. Bronchial Blocker Use in the Difficult Airway Patient Requiring Lung Isolation: Clarification as to What Blockers Are Actually Available. Anesth Analg. 2018 Sep 24. doi: 10.1213/ANE.0000000000003799. [Epub ahead of print] No abstract available.

Volume 2, Issue 37 - September 23, 2018

CSP News of the Week

The First CSP Visiting Professor of the Season. Please join us this Wednesday September 26, 2018 at 4:00 PM at the Sam Cohen Auditorium, Albrechtsen Research Centre for the Cardiac Sciences Program’s monthly Visiting Professor Series Lecture. Dr. Peter Brindley from the University of Alberta will be our first guest of the season. Join us at 4PM for his talk.... “Burnout, Resilience and Beyond: getting past the platitudes” followed by a reception in the Atrium from 5-6 PM. Hope to see you there!

Shoutouts

Congrats to Dr. Andrew Morris and the entire CPD team for another memorable Cardiology Day event..and thanks to all of you that participated in the event (including me :-).

Publications by our Faculty this Week

There were no new publications this week


Volume 2, Issue 36 - September 15, 2018

What is the Shared Health Initiative? What will be its impact on the Cardiac Sciences Program?

Along with most of the CSP leadership, I attended the Shared Health provincial planning workshop on Friday. As you know, this initiative aims to redraw the framework for the delivery of clinical and preventive services across Manitoba. Those aims are convergent with the goals of the CSP in the context of our services- both diagnostic and consultative. The kickoff of Shared Health is especially timely given our current efforts, under the leadership of Essi Shams (our Manager of QI and Patient Safety), to map out the patient journeys for our 6 major clinical programs and to establish new, more efficient and effective pathways for them-- featuring a much expanded role for our “access office”.

We will have important roles in shaping Shared Health’s vision for cardiac services. I co-chair the Cardio-Thoracic- Vascular Provincial Clinical Team (PCT)- joined by the CSP leadership and I also serve on the Integrated Leadership Team (that the PCT’s report to). Together, we look forward to updating you (and getting your input) on the Shared Health planning process as it impacts on the CSP as we progress down this road. Stay tuned.

CSP News of the Week!

Congratulations to Brett Hiebert and his wife Dayna on the arrival of their baby boy, Blake William Orion Hiebert who was born on September 1, 2018 at 3:28 AM weighing in at 8lbs 6oz.

Congratulations to Dr. Mike Yamashita and his wife Meme on the arrival of their baby boy (still working on the name) Friday September 14, 2018 at 7:16 AM weighting in at 6lbs 8oz.

Publications by our Faculty this Week

Schultz ASH, Dahl L, McGibbon E, Brownlie RJ, Cook C, Elbarouni B, Katz A, Nguyen T, Sawatzky JA, Sinclaire M, Throndson K, Fransoo R. Index coronary angiography use in Manitoba, Canada: a population-level descriptive analysis of First Nations and non-First Nations recipients. BMJ Open. 2018 Mar 25;8(3):e020856. doi: 10.1136/bmjopen-2017-020856.

Lodewyks C, Heinrichs J, Grocott HP, Karkouti K, Romund G, Arora RC, Tangri N, Rabbani R, Abou-Setta A, Zarychanski R. Point-of-care viscoelastic hemostatic testing in cardiac surgery patients: a systematic review and meta-analysis. Can J Anaesth. 2018 Sep 7. doi: 10.1007/s12630-018-1217-9. [Epub ahead of print]

Navarrete M, Ho J, Dwivedi RC, Choi N, Ezzati P, Spicer V, Arora RC, Rigatto C, Wilkins JA. Activity-based protein profiling of intraoperative serine hydrolase activities during cardiacsurgery. J Proteome Res. 2018 Sep 7. doi: 10.1021/acs.jproteome.8b00500. [Epub ahead of print]

Choi N, Whitlock R, Klassen J, Zappitelli M, Arora RC, Rigatto C, Ho J. Early intraoperative iron-binding proteins are associated with acute kidney injury after cardiac surgery. J Thorac Cardiovasc Surg. 2018 Jul 27. pii: S0022-5223(18)32021-X. doi: 10.1016/j.jtcvs.2018.06.091. [Epub ahead of print]

Zelenitsky SA, Calic D, Arora RC, Grocott HP, Lakowski TM, Lillico R, Ariano RE. Antimicrobial Prophylaxis for Patients Undergoing Cardiac Surgery: Intraoperative Cefazolin Concentrations and Sternal Wound Infections. Antimicrob Agents Chemother. 2018 Aug 27. pii: AAC.01360-18. doi: 10.1128/AAC.01360-18. [Epub ahead of print]

Kredentser MS, Blouw M, Marten N, Sareen J, Bienvenu OJ, Ryu J, Beatie BE, Logsetty S, Graff LA, Eggertson S, Sweatman S, Debroni B, Cianflone N, Arora RC, Zarychanski R, Olafson K. Preventing Posttraumatic Stress in ICU Survivors: A Single-Center Pilot Randomized Controlled Trial of ICU Diaries and Psychoeducation. Crit Care Med. 2018 Aug 16. doi: 10.1097/CCM.0000000000003367. [Epub ahead of print]


Volume 2, Issue 35 - September 8, 2018

Publications by our Faculty this Week

Islam MA, Ravandi A, Aukema HM. Linoleic acid derived oxylipins are elevated in kidney and liver and reduced in serum in rats given a high-protein diet. J Nutr Biochem. 2018 Aug 15;61:40-47. doi: 10.1016/j.jnutbio.2018.07.015. [Epub ahead of print]

Mutch WAC, El-Gabalawy R, Girling L, Kilborn K, Jacobsohn E. End-Tidal Hypocapnia Under Anesthesia Predicts Postoperative Delirium. Front Neurol. 2018 Aug 17;9:678. doi: 10.3389/fneur.2018.00678. eCollection 2018.

Grocott HP. The second report of bilateral hand transplantation in a child. Lancet Child Adolesc Health. 2017 Dec;1(4):e3. doi: 10.1016/S2352-4642(17)30131-1. Epub 2017 Nov 15. No abstract available.

Volume 2, Issue 34 - August 31, 2018

Shout Outs

Congratulations to Dr. Ashish Shah, Dr. Malek Kass and Dr. Nasir Shaikh. This week they performed their first trans-catheter paravalvular leak closure. They hope to provide this structural interventional servicer to many more patients in Manitoba.

Publications by our Faculty this Week

Cloutier JM, Khoo C, Hiebert B, Wassef A, Seifer CM. Physician decision making in anticoagulating atrial fibrillation: a prospective survey of a physician notification system for atrial fibrillation detected on cardiac implantable electronic devices of patients at increased risk of stroke. Ther Adv Cardiovasc Dis. 2018 Apr;12(4):113-122. doi: 10.1177/1753944717749739.

Mazer CD, Whitlock RP, Fergusson DA, Belley-Cote E, Connolly K, Khanykin B, Gregory AJ, de Médicis É, Carrier FM, McGuinness S, Young PJ, Byrne K, Villar JC, Royse A, Grocott HP, Seeberger MD, Mehta C, Lellouche F, Hare GMT, Painter TW, Fremes S, Syed S, Bagshaw SM, Hwang NC, Royse C, Hall J, Dai D, Mistry N, Thorpe K, Verma S, Jüni P, Shehata N; TRICS Investigators and Perioperative Anesthesia Clinical Trials Group. Six-Month Outcomes after Restrictive or Liberal Transfusion for Cardiac Surgery. N Engl J Med. 2018 Aug 26. doi: 10.1056/NEJMoa1808561. [Epub ahead of print]

Zelenitsky SA, Calic D, Arora RC, Grocott HP, Lakowski TM, Lillico R, Ariano RE. Antimicrobial Prophylaxis for Patients Undergoing Cardiac Surgery: Intraoperative Cefazolin Concentrations and Sternal Wound Infections. Antimicrob Agents Chemother. 2018 Aug 27. pii: AAC.01360-18. doi: 10.1128/AAC.01360-18. [Epub ahead of print]

Muller Moran HR, Kass M, Ravandi A, Zieroth S, Schaffer SA, Cordova FJ, Pozeg ZI, Arora RC, Singal RK. Diagnosis of Left Ventricular Assist Device Outflow Graft Obstruction Using Intravascular Ultrasound. Circ Heart Fail. 2016 Dec;9(12). pii: e003472. No abstract available.]


Volume 2, Issue 33 - August 26, 2018

CSP in the News

Notably the initial focus of the Free Press was to highlight the lengthening echo waitlist. However, the interview occurred (fortunately) shortly after our request to extend echo services had been approved. We are still working out the details on how this will be implemented. See article by clicking HERE

Publications by our Faculty this Week

Kredentser MS, Blouw M, Marten N, Sareen J, Bienvenu OJ, Ryu J, Beatie BE, Logsetty S, Graff LA, Eggertson S, Sweatman S, Debroni B, Cianflone N, Arora RC, Zarychanski R, Olafson K. Preventing Posttraumatic Stress in ICU Survivors: A Single-Center Pilot Randomized Controlled Trial of ICU Diaries and Psychoeducation. Crit Care Med. 2018 Aug 16. doi: 10.1097/CCM.0000000000003367. [Epub ahead of print]


Volume 2, Issue 32 - August 19, 2018

CSP in the News

Does having a female physician in the ED on the case improve prognosis of women with STEMI? Based on the reporting around a recent PNAS paper that asked that question we had the opportunity to remind viewers of the ongoing care gap in the management of heart disease in women. The link to the CTV story is below. https://winnipeg.ctvnews.ca/video?clipId=1456454

Publications by our Faculty this Week

Jones PJH, Shamloo M, MacKay DS, Rideout TC, Myrie SB, Plat J, Roullet JB, Baer DJ, Calkins KL, Davis HR, Barton Duell P, Ginsberg H, Gylling H, Jenkins D, Lütjohann D, Moghadasian M, Moreau RA, Mymin D, Ostlund RE Jr, Ras RT, Ochoa Reparaz J, Trautwein EA, Turley S, Vanmierlo T, Weingärtner O. Progress and perspectives in plant sterol and plant stanol research. Nutr Rev. 2018 Aug 7. doi: 10.1093/nutrit/nuy032. [Epub ahead of print]


Volume 2, Issue 31 - August 12, 2018

CSP Annoucements

This week we wish farewell and every success to Kim Kummen, Administrative Director, who departs to assume the senior financial management role for the Grace Hospital. Kim has been instrumental in helping to guide the Cardiac Sciences Program through Phase 1 and Phase 2 of the consolidation of acute care services in Winnipeg as well as helping us to avoid "ditches" with the day-to-day bumps in the road that are the norm for us. Good luck Kim. You will be remembered (and missed).

Please join us in welcoming our new Interventional Cardiology fellow, Dr. Karthik Balasubramaniam, who started his fellowship on August 7, 2018.

Publications by our Faculty this Week

Ibrahim OA, Drew D, Hayes CJ, McIntyre W, Seifer CM, Hopman W, Glover B, Baranchuk AM. Implantable loop recorders in the real world: a study of two Canadian centers. J Interv Card Electrophysiol. 2017 Nov;50(2):179-185. doi: 10.1007/s10840-017-0294-y. Epub 2017 Nov 2.

Grocott HP Emergence delirium and intranasal dexmedetomidine: The importance of method, dosing, and timing of administration. Int J Pediatr Otorhinolaryngol. 2018 Sep;112:210. doi: 10.1016/j.ijporl.2018.03.021. Epub 2018 Mar 23.


Volume 2, Issue 30 - August 5, 2018

CSP PILOT PROJECT SUPPORT PROGRAM WILL BE OPEN FOR APPLICATIONS BY AUGUST 15

The CSP will be initiating a pilot project competition with application forms and guidelines available within 2 weeks. This competition will feature support for:
• Research Development Grants of up to $25,000 each
• Innovations in Medical Education and KT Grants of up to $25, 000 each.
This competition will be open to all areas of scholarship within the Cardiac Sciences Program. The application form will be short (2 page limit on the proposal). Notably, PI and co-PI from each project must be from 2 different sections of the CSP. The application deadline will be at the end of September.

CSP SEEKING NOMINATIONS FOR 2018 HEALTH INNOVATION AWARDS: Awards Focus on Improving Patient Care and Advocating Healthy Living

This year’s province-wide awards recognize and celebrate health care system initiatives across the province in four categories:
• patient-centred care, to recognize an initiative that directly results in improved processes, clinical approaches and the culture of patient-centred care in front-line services, such as access to care, quality of care and overall patient experience;
• health system improvement, to recognize creative and pioneering efforts that have resulted in process improvements;
• the Mino Bimaadiziwin Innovation Award for Healthy Living, to recognize an individual or group that has enhanced healthy living activities among Manitobans; and
• the Enid Thompson Award for Health Care Innovation, to recognize an individual who initiated outstanding change that has had a positive effect on patient care in the publicly funded health-care system.

Nominees will demonstrate how their work has advanced and improved care, and how they are sharing what they learned within Manitoba to ensure long-term success.
We are looking to submit one nomination from the Cardiac Sciences Program.
If you have an idea for a nomination (and would be willing to do some of the legwork to support your nominee) get your suggestion to me asap.

More information on the awards and nomination instructions are available at www.gov.mb.ca/health/awards. Nominations will be accepted until Sept. 17 and the winners will be announced later this year.

Publications by our Faculty this Week

Grocott HP. Additional concerns for the scavenging of anesthetic agents used for ICU sedation. J Clin Monit Comput. 2018 Aug 1. doi: 10.1007/s10877-018-0191-7. [Epub ahead of print] No abstract available.

Solati Z, Edel AL, Shang Y, O K, Ravandi A. Oxidized phosphatidylcholines are produced in renal ischemia reperfusion injury. PLoS One. 2018 Apr 23;13(4):e0195172. doi: 10.1371/journal.pone.0195172. eCollection 2018.