Position: Professor

Office:
University of Manitoba
Department of Human Nutritional Sciences
R 203, Richardson Centre for Functional Foods and Nutraceuticals
196 Innovation Drive
Winnipeg, MB R3T 6C5 Canada

Phone No.: (204) 474-8682

Fax No.: (204) 474-7552

E-mail: james.friel@ad.umanitoba.ca

Dr. Friel works primarily with infant nutrition focusing on mother's milk. His research program looks for new bioactive molecules in mother's milk that may be applied to other areas of the life cycle.

Education:

B.Sc. Concordia
M.Sc. University of Saskatoon
Ph.D. University of Guelph

Areas of Specialization:

• Nutritional Science
• Antioxidants in health and disease
• Infant nutrition

Research Interests:

• Infant Nutrition: Effects of nutrient intervention
• Antioxidants: Antioxidant properties of nutrients
• Health and Chronic Diseases: Role of nutrients, neutraceuticals and functional foods

Selected Publications:

Abramovich M, Miller A, Yang H, Friel JK. Molybdenum content of Canadian and US infant formulas. Biol Trace Elem Res. 2011;143(2):844-53.

Elisia I, Tsopmo A, Friel JK, Diehl-Jones W, Kitts DD. Tryptophan from human milk induces oxidative stress and upregulates the nrf-2-mediated stress response in human intestinal cell lines. J Nutr. 2011;141(8):1417-23.

Tsopmo A, Romanowski A, Banda L, Lavoie JC, Jenssen H, Friel JK. Novel anti-oxidative peptides from enzymatic digestion of human milk. Food Chem. 2011;126(3):1138-43.

Pripotnev S, Tsopmo A, Friel JK, Ianoul A. UV resonance raman spectroscopy probes the amide II'p band position in short breast milk peptides with antioxidant activity. J Raman Spectrosc. 2011.

Friel JK, Diehl-Jones B, Cockell KA, Chiu A, Rabanni R, Davies SS, et al. Evidence of oxidative stress in relation to feeding type during early life in premature infants. Pediatr Res. 2011;69(2):160-4.

Chessex P, Watson C, Kaczala GW, Rouleau T, Lavoie M-, Friel J, et al. Determinants of oxidant stress in extremely low birth weight premature infants. Free Radical Biology and Medicine. 2010;49(9):1380-6.

Li W, Friel J, Beta T. An evaluation of the antioxidant properties and aroma quality of infant cereals. Food Chem. 2010;121(4):1095-102.

Friel JK, Hanning RM, Isaak CA, Prowse D, Miller AC. Canadian infants' nutrient intakes from complementary foods during the first year of life. BMC Pediatrics. 2010;10.

Singh AJ, Bronshtein V, Khashu M, Lee K, Potts JE, Friel J, et al. Vitamin A is systemically bioavailable after intratracheal administration with surfactant in an animal model of newborn respiratory distress. Pediatr Res. 2010;67(6):619-23.

Orozco MN, Solomons NW, Schümann K, Friel JK, De Montenegro ALM. Antioxidant-rich oral supplements attenuate the effects of oral iron on in situ oxidation susceptibility of human feces. J Nutr. 2010;140(6):1105-10.

Yao L, Friel JK, Suh M, Diehl-Jones WL. Antioxidant properties of breast milk in a novel in vitro digestion/enterocyte model. J Pediatr Gastroenterol Nutr. 2010;50(6):670-6.

Tsopmo A, Diehl-Jones BW, Aluko RE, Kitts DD, Elisia I, Friel JK. Tryptophan released from mother's milk has antioxidant properties. Pediatr Res. 2009;66(6):614-8.

Tijerina Sáenz A, Elisia I, Innis SM, Friel JK, Kitts DD. Use of ORAC to assess antioxidant capacity of human milk. Journal of Food Composition and Analysis. 2009;22(7-8):694-8.

Nayak BN, Friel JK, Rempel CB, Jones PJH. Energy-restricted diets result in higher numbers of CD4+, CD8+, immunoglobulins (A, M, and G), and CD45RA cells in spleen and CD4+, immunoglobulin A, and CD45RA cells in colonic lamina propria of rats. Nutr Res. 2009;29(7):487-93.

Li W, Hosseinian FS, Tsopmo A, Friel JK, Beta T. Evaluation of antioxidant capacity and aroma quality of breast milk. Nutrition. 2009;25(1):105-14.

Merrells KJ, Friel JK, Knaus M, Suh M. Following 2 diet-restricted male outdoor rock climbers: Impact on oxidative stress and improvements in markers of cardiovascular risk. Applied Physiology, Nutrition and Metabolism. 2008;33(6):1250-6.

Lavoie J-, Rouleau T, Tsopmo A, Friel J, Chessex P. Influence of lung oxidant and antioxidant status on alveolarization: Role of light-exposed total parenteral nutrition. Free Radical Biology and Medicine. 2008;45(5):572-7.

Barceló-Coblijn G, Murphy EJ, Othman R, Moghadasian MH, Kashour T, Friel JK. Flaxseed oil and fish-oil capsule consumption alters human red blood cell n-3 fatty acid composition: A multiple-dosing trial comparing 2 sources of n-3 fatty acid. Am J Clin Nutr. 2008;88(3):801-9.

Diehl-Jones WL, Askin DF, Friel JK. Microlipid-induced oxidative stress in human breastmilk: In vitro effects on intestinal epithelial cells. Breastfeeding Medicine. 2007;2(4):209-17.

Harrison A, Khashu M, Friel J, Lavoie J-, Chessex P. Variations in metabolic response to TPN are influenced more by sex than by light exposure. J Pediatr Gastroenterol Nutr. 2007;45(5):577-81.

Hosseinian FS, Li W, Hydamaka AW, Tsopmo A, Lowry L, Friel J, et al. Proanthocyanidin profile and ORAC values of manitoba berries, chokecherries, and seabuckthorn. J Agric Food Chem. 2007;55(17):6970-6.

Lavoie J-, Chessex P, Rouleau T, Tsopmo A, Friel J. Shielding parenteral multivitamins from light increases vitamin A and E concentration in lung of newborn guinea pigs. Clinical Nutrition. 2007;26(3):341-7.

Friel JK, Diehl-Jones WL, Suh M, Tsopmo A, Shirwadkar VP. Impact of iron and vitamin C-containing supplements on preterm human milk: In vitro. Free Radical Biology and Medicine. 2007;42(10):1591-8.

Tsopmo A, Friel JK. Human milk has anti-oxidant properties to protect premature infants. Current Pediatric Reviews. 2007;3(1):45-51.