Position: Professor and Head of Department

Office:
University of Manitoba
Department of Human Nutritional Sciences
W379 Duff Roblin Building
Winnipeg, MB R3T 2N2 Canada

Phone No.: (204) 474-6837

Fax No.: (204) 474-7593

E-mail: james.house@ad.umanitoba.ca

Dr. House is studying the relationship between water soluble vitamin nutrition, the metabolism of amino acids, and how they relate to optimal growth and health of individuals. He also maintains a strong focus towards the development of functional foods of animal origin, including eggs with enhanced nutritional value.

Education:

Ph.D. University of Guelph

Research Interests

• Determination of the protein quality of foods and food ingredients
• Regulation of the nutrient/bioactive content of eggs
• Nutritional regulation of sulphur amino acid metabolism
• Water-soluble vitamin nutrition

Research Affiliations

• Richardson Centre for Functional Foods and Nutraceuticals
• Canadian Centre for Agri-Food Research in Health and Medicine
• Department of Animal Science, University of Manitoba
• Département des sciences des aliments et de nutrition, Université Laval

Selected Publications:

Munyaka P.M., Tactacan G., Jing, M., O, K., House J.D., St. Paul, M., Sharif, S. and Rodriguez-Lecompte J.C.  Response of old laying hens to an Escherichia coli lipopolysaccharide challenge when fed diets with or without supplemental folic acid.  Poult. Sci. (In Press)

Munyaka P., Yitbarek, A., Echeverry, H., Camelo-Jaimes, G., Sharif, S., Guenter, W., House J.D., and Rodriguez-Lecompte, J.C.  2012.  Local and systemic innate immunity in broiler chickens supplemented with yeast-derived carbohydrates.  Poult. Sci. 91: 2164-2172.

Munyaka P., Tactacan G., Jing, M., O K., House J.D., and Rodriguez-Lecompte J.C. 2012.  Immunomodulation in young laying hens by dietary folic acid and systemic acute immune response after challenge with Escherichia coli lipopolysaccharide. Poult. Sci 91: 2454-2463.

Gakhar, N., Goldberg, E., Jing, M., Gibson, R., and House, J.D.  2012.  Effect of feeding hempseed and hempseed oil on performance and measures of lipid metabolism in laying hens.  Poult. Sci.  91: 701-711.

Goldberg,E., Gakhar, N., Ryland, D., Aliani, M., Gibson, R., and House, J.D. 2012.  Fatty acid profile and sensory characteristics of table eggs from laying hens fed hempseed and hempseed oil.  J. Food Sci. 77: S153-160

Rodriguez-Lecompte, J.C., Yitbarek, A., Brady, J., Sharif, S., Cavanagh, M.D., Crow, G., Guenter, W., House, J.D., and Camelo-Jaimes, G. 2012.  The effect of microbial-nutrient interaction on the immune system of young chicks following early probiotic and organic acids administration. J. Anim. Sci. 90: 2246-2254.

Yitbarek, A., Echeverry, H., Brady, J., Hernandez-Doria, J., Camelo-Jaimes, G., Sharif, S., Guenter, W., House, J.D., and Rodriguez-Lecompte, J.C. 2012.  Innate immune response to yeast-derived carbohydrates in broiler chickens fed organic diets and challenged with Clostridium perfringens.  Poult. Sci.  91: 1105-1112.

Tactacan, G.B., Rodriguez-Lecompte, J.C., O, K. and House, J.D. 2011.  The regulation of folate absorption in the intestine of the laying hen with increased dietary folic acid supplementation. Poult. Sci.  91:121-128.

Neijat, M., House, J.D., Guenter, W., and Kebreab, E.  Calcium and phosphorus dynamics in commercial laying hens housed in either conventional or enriched cage systems.   Poult. Sci.  90: 2383-2396.

Wakefield, A.P., House, J.D., Ogborn, M.R, Weiler, H.A., Aukema, H.M.  2011.  A high protein diet at the upper end of the acceptable macronutrient distribution range (AMDR) leads to kidney damage in normal female rats.  Brit. J. Nutr. 106: 656-663. (NSERC)

Hebert, K., Tactacan, G., Dickson, T.M, Guenter, W., and House, J.D.   2011.  The effect of cereal type and exogenous enzyme use on total folate content of eggs from laying hens consuming diets supplemented with folic acid.  J. Appl. Poult. Res. 20:  303-312.

Tactacan, G.B., Rodriguez-Lecompte, J.C., O, K. and House, J.D. 2011.  Functional characterization of folic acid transport in the intestine of the laying hen.  Poult. Sci. 90: 83-90. (NSERC CRD)
Hwang, S.Y, Siow, Y.L., Au-Yeung, K.K., House, J. and O, K. 2011.  Folic acid supplementation inhibits NADPH oxidase-mediated superoxide anion production in the kidney. Am. J. Physiol. Ren. Physiol. 300:  F189-F198. (NSERC)

Neijat, M., House, J.D., Guenter, W., and Kebreab, E.  2011.  Production performance and nitrogen balance of Shaver White layers housed in enriched or conventional caged systems.  Poult. Sci. 90: 543-554

Dickson, T.M., Tactacan, G., Hebert, K., Guenter, W., and House, J.D. 2010.  Optimization of folate deposition in eggs through dietary supplementation of folic acid over the entire production cycle of Hyline W36, Hyline W98 and CV20 laying hens.  J. Appl. Poult. Res. 19: 80-91.

Lawlor, J.B., Gaudette, N., Dickson, T., and House, J.D.  2010.  Fatty acid profile and sensory characteristics of table eggs from laying hens fed diets containing microencapsulated fish oil.  Anim. Feed Sci. Tech. 156: 97-103.

Tactacan, G. B., Jing, M., Thiessen, S., O’Connor, D. L., Rodriguez-Lecompte, J. C., Guenter,W., and House, J.D. 2010.  Characterization of folate-dependent enzymes and indices of folate status in laying hens supplemented with dietary folic acid or 5-methyltetrahydrofolate.  Poult. Sci. 89:  688-696. (NSERC CRD)

Kannampuzha, J., Donnelly, S., McFarlane, P., Chan, C.T., Pencharz, P.B., and House, J.D., and Darling, P.B. 2010. Glutathione and riboflavin status in patients undergoing home nocturnal hemodialysis versus standard hemodialysis.  J. Renal Nutr. 20: 199-208.

Jia, Y., Hwang, S.Y., House, J.D., Ogborn, M.R., Weiler, H.A., O, K., and Aukema, H.M.  2010.  Long-term high intake of whole proteins results in renal damage in the pig.  J. Nutr. 140: 1646-1652. (NSERC)

Jing, M., Tactacan, G.B., Rodriguez-Lecompte, J.C., Kroeker, A., and House, J.D.  2010. Proton-Coupled Folate Transporter (PCFT):  Molecular cloning, tissue expression patterns and effects of dietary folate supplementation on mRNA expression in laying hens.  Brit. Poult. Sci. 51: 635-638.

House, J.D., Neufeld, J., and Leson, G. 2010. Evaluating the quality of protein from hemp seed and hemp seed products through the use of the protein digestibility-corrected amino acid score method. J. Agric. Food Chem.58: 11801-11807.

Bhandari, S.K., House, J.D., Nyachoti, C.M, and Krause D.O.  2010.  Response of nursery pigs to a synbiotic based on starch (prebiotic) and an anti-Escherichia coli K88 probiotic.  Appl. Environ. Microbiol. 76: 8192-8200.

Brady, J., Hernandez-Doria, J.D., Bennett, C., Guenter, W., House, J.D., and Rodríguez-Lecompte, J.C. 2010.  Toxinotyping of necrotic enteritis-producing and commensal isolates of Clostridium perfringens from chickens fed organic diets.  Avian Path.  39: 475-481.

Liu, X, Zhao, H., Thiessen, S., House, J.D., and Jones, PJH.  2010.  Effect of plant sterol enriched diets on plasma and egg yolk cholesterol concentrations and cholesterol trafficking in laying hens. Poult. Sci. 89:  270-275

Pye, K.M., Wakefield, A., Aukema, H.M., House, J.D., Ogborn, M., and Weiler, H.A. 2009.  A high mixed protein diet reduces body fat without altering the mechanical properties of bone in female rats.  J. Nutr. 139:2099-2105. (NSERC)

Rafii M., Elango R., House, J.D., Courtney-Martin, G., Darling, P., Fisher, L., Pencharz, P.B.  2009.  Measurement of homocysteine and related metabolites in human plasma and/or urine by liquid chromatography-electrospray tandem mass spectrometry.  J. Chromatogr. B. 877: 3282-3291 (Invited Review)(NSERC)

Setia A., Bhandari, S.K., House, J.D., Nyachoti, C.M, and Krause D.O. 2009. Development and in vitro evaluation of an Escherichia coli probiotic able to inhibit the growth of pathogenic E. coli K88. J Anim Sci. 87: 2005-2012.

Jing, M., Tactacan, G.B., Rodriguez-Lecompte, J.C., Kroeker, A., House, J.D.  2009. Molecular cloning and tissue distribution of reduced folate carrier (RFC) and effect of dietary folate supplementation on the expression of RFC in laying hens.  Poultry Sci. 88:1939-1947.

Tactacan, G., Lewis, N.J., Rodriquez-Lecompte, J.C., Guenter, W., and House, J.D.  2009. Comparison of indices of health, welfare and productivity of laying hens housed in two different commercial cage designs.  Poultry Sci. 88:698-707.

Shuaibi, A., Sevenhuysen, G., and House, J.D.  2009.   The comparison of folate intake data estimated on the basis of two different databases:  Results and experiences.  J. Food Comp. Anal. 22: 38-43.

Zhang, Z., Kebreab, E., Jing, M., Kuehn, R., Flintoft, M., and House, J.D.  2009.  Impairments in pyridoxine-dependent sulphur amino acid metabolism are highly sensitive to the degree of vitamin B6 deficiency and repletion in the pig.  Animal  3: 826-837.(NSERC)