University of Manitoba - Faculty of Medicine - Internal Medicine

Research Groups

A research group is an association of University scholars who share research interests and who engage in collaborative or closely related research activities. The purpose of a research group is to promote and facilitate communication and collaboration among its members and to establish the legitimacy of the group both inside and outside the University.

Research groups include:

Diabetes Research Group
IBD Clinical and Research Centre/Gastroenterology
Liver Diseases Research Group
Manitoba Centre for Proteomics and Systems Biology

While not formally recognized as a group, members of the Section of Rheumatology and Nephrology are actively involved in basic and clinical research.

Diabetes Research Group

Members of this group include:
Dr. Gregoire Nyomba	Internal Medicine
Dr. Sora Ludwig	Internal Medicine
Dr. Garry Shen	Internal Medicine
Dr. Vincent Woo	Internal Medicine
Dr. Heather Dean	Pediatrics & Child Health
Dr. Elizabeth Sellers	Pediatrics & Child Health
Dr. Shayne Taback	Pediatrics & Child Health

The objective of the Diabetes Research Group is to provide both basic and clinical research in the area of diabetes research. The research group has a core of successful investigators who have received recognition nationally and internationally through competitive research funding and clinical contracts.

IBD Clinical and Research Centre/Gastroenterology

Members of this group include:
Dr. Charles Bernstein	Internal Medicine
Dr. Michael Cantor	Internal Medicine
Dr. Donald Duerksen	Internal Medicine
Dr. Alexandra Ilnyckyj	Internal Medicine
Dr. Teresa Longobardi	Internal Medicine
Dr. Harminder Singh	Internal Medicine
Dr. Laura Targownik	Internal Medicine
Dr. James Blanchard	Community Health Sciences
Dr. Denis Krause	Animal Science

Established in 1994, the IBD Clinical and Research Centre has received international attention and recognition. It has the largest IBD database in North America. In collaboration with researchers at John Hopkins University, this research group is studying the prevalence of NOD₂ gene abnormalities in Manitobans with Crohn's Disease.

Liver Diseases

Members of this group include:
Dr. Gerald Minuk	Internal Medicine
Dr. Kelly Kaita	Internal Medicine
Dr. Julia Rempel	Internal Medicine
Dr. Julia Uhanova	Internal Medicine
Dr. Steven Wong	Internal Medicine
Dr. Frank Burczynski	Pharmacy
Dr. Yuewen Gong	Pharmacy
Dr. Wayne Lautt	Pharmacology

The principle goal of the liver diseases research group is to enhance the understanding and thereby develop more effective therapy for inflammatory disorders of the hepatobiliary system. Much of the research being performed employs recombinant DNA physiology, animal models and patients with viral hepatitis. The results are relevant to other common liver disorders including alcoholic hepatitis, fatty liver, drug induced hepatitis, primary bilary cirrhosis and primary sclerosing cholangitis.

Ongoing collaboration with other groups further contribute to the success of this program. For example, colleagues in pathology have documented the appearance and nature of the inflammatory cells as well as the magnitude of the reparative processes by advanced immunocytochemical and electron microscope techniques, while colleagues in radiology are assessing the severity of diseases and rapidity of its resolution by standard radiologic studies and MRI.

Manitoba Centre for Proteomics and Systems Biology (MCPSB)

Members of this group include:
Dr. John Wilkins	Internal Medicine
Dr. Hani El-Gabalawy	Internal Medicine
Dr. Peter Nickerson	Internal Medicine
Dr. Peter Cattini	Physiology/Pharmacology
Dr. Kevin Coombs	Medical Microbiology
Dr. Jim Davie	Biochemistry and Molecular Biology
Dr. Harry Duckworth	Chemistry
Dr. Werner Ens	Physics & Astronomy
Dr. Elissavet Kardami	Human Anatomy & Cell Sciences
Dr. Jim Nagy	Physiology
Dr. Geoff Hicks	Biochemistry & Medical Genetics
Dr. Helene Perreault	Chemistry
Dr. Ken Standing	Physics and Astronomy

The objective of the MCPSB is to provide core expertise and services in several areas of relevance to the biological and medical research community in Manitoba and Canada. These areas include but are not limited to bioinformatics, proteomics, protein separation, mass spectrometry, monoclonial antibody production and high content image analysis.

The MCPSB is dedicated to research involving the analysis and functional characterisation of proteins in the context of the organism. This includes the application and development of approaches for isolation, identification and characterisation of proteins and their interactions in health and disease.