Clinical Bacteriology MMIC 7040
Full Course: 6 credit hours - Minimum 4-5 students; Maximum 9-10
Coordinator:  Philippe Lagacé-Wiens, MD, DTM&H, FRCPC
Telephone: 204. 237-2483
Email: plagacewiens@dsmanitoba.ca
Schedule:  One 2-hour class per week, both terms. 
Held Wednesday mornings 9 - 11 a.m. 
Assigned readings provided.
Location:  Room 540 - Basic Medical Sciences Building
Start Date: September 18, 2013 
Prerequisite: Instructor permission required
Evaluation:  Written Examination*, Part 1, end of first term, 40%
Written Examination*, Part 2, end of second term 60%
Students have the option of submitting a written term paper due February 28, 2014, for a value of 20% (Part 1 exam 30%; Part 2 exam 50%)
*Royal College style short answer and multiple choice. 
Description:  The course begins with introductory lectures reviewing the laboratory methods in use in modern diagnostic laboratories.  Following this, each of the major bacterial pathogens affecting humans is reviewed in a two hour lecture. At each lecture the taxonomy, structure, epidemiology, virulence factors, clinical presentations of infection, diagnosis and detection, treatment and prevention are discussed for each. A separate series of lectures discusses also the role and mechanisms of common antimicrobial resistance in bacteria.  For each lecture, students will also be responsible for the provided handouts as potential exam material.
Objective:  Designed to provide students with a clear entry to mid-level understanding of the clinical and diagnostic issues in bacteriology, the course should be used as an introduction to more advanced study in infectious diseases and clinical microbiology.

Required Text:

 

 ASM manual of Clinical Microbiology (10th Ed.);
http://estore.asm.org/browse/index.asp?plid=2&categoryid=18

Optional Text:

 

 Washington C Winn Jr, MD, Stephen D Allen MD, William M Janda PhD, et al.Koneman's Color Atlas and Textbook of Diagnostic Microbiology available at: http://www.lww.com/
N.B.: New edition expected November 2013.

Course Outline

 Topics:
   1. Bacterial Structure
   2. Methods of Molecular Microbiology and Microscopy
   3. Biosafety, Specimen Collection and Transport
   4. Staphylococcus aureus
   5. Coagulase-negative Staphylococcus
   6. b-hemolytic Streptococcus
   7. a-hemolytic Streptococcus and S. pneumoniae
   8. Enterococcus
   9. Neisseria gonorrheae
 10. Neisseria meningitidis and Moraxella catharrhalis
 11. Mycoplasmas
 12. Chlamydia and Rickettsias
 13. Campylobacter, Helicobacter, Vibrio
 14. Gram-positive Bacilli (Listeria, Corynebacterium)
 15. Bacteroides and Gram-negative Anaerobes
 16. Clostridium and Gram-positive Anaerobes
 17. Enterobacteriaceae and E. coli
 18. Shigella and Salmonella
 19. Hemophilus and other fastidious Gram-negatives
 20. Mycobacterium
 21. Pseudomonas and the non-fermenters
 22. Treponemes (Lyme disease and syphilis)
 23. Legionella and Miscellaneous organisms (Bardetella, Brucella and Francisella)
 24. Bacillus
 25. Antimicrobics and resistance
 26. Antimicrobics and resistance
 27. Antimicrobics and resistance

*Please note that this will be the first year that Dr. Lagacé-Wiens takes over instructing this course from the previous person. Outlines and availability is subject to change.

Graduate Pogram Coordinator:
Angela Nelson 204-789-3444
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