Dr. Linda Larcombe
 
Assistant Professor, Department of Internal of Medicine, University of Manitoba

Degrees: Ph.D.

Mailing Address: Department of Medical Microbiology 745 Bannatyne Avenue, Room 503 Winnipeg, MB R3E 0J9

Tel: (204) 789-1051 Fax: (204) 789-1198
E-mail: llarcombe@hsc.mb.ca
Research Interests:
My research is focused on the study of genetic, socio-cultural and environmental factors contributing to infectious disease susceptibility and resistance in Canadian Aboriginal populations. Trained in anthropology, my approach to infectious disease research is multidisciplinary and draws from medical anthropology, immunogenetics, immunology, ancient DNA , geographic information systems, land use studies, history and archaeology to gain new perspectives regarding disease susceptibility and resistance.

Recent Publications:

  1. Larcombe, L., Nickerson, P., Dembinski, I., Lodge, A., Larcombe, E., Milligan, L., Martin, B. and Orr, P. - 2008 Functional gene polymorphisms in Canadian Aboriginal populations with high rates of tuberculosis Journal of Infectious Diseases Vol. 198

  2. Canadian Tuberculosis Committee. - 2007 Housing conditions which serve as risk factors for tuberculosis infection and disease. An Advisory Committee Statement prepared for the Canadian Tuberculosis Committee by L. Larcombe and P. Orr. Canadian Communicable Disease Report . Vol. 33

  3. Larcombe, L. Waruk, J., Schellenberg, J., Ormond, M. - 2007 Rapid emergence of MRSA among children and adolescents in northern Manitoba, 2003-2006 Canadian Communicable Disease Report Vol. 33–02.

  4. Larcombe, L., Nickerson, P., Hoppa, R.D. and Matheson, C. - 2005 Detection of a single nucleotide polymorphism in the IL-6 promoter region of ancient nuclear DNA . Infection, Genetics and Evolution. Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases Vol. 5 (2): 117-122

  5. Larcombe, L., Rempel, J., Dembinski, I., Tinckam, K., Rigatto, C. and Nickerson, P. - 2005 Differential cytokine genotype frequencies among Canadian Aboriginal and Caucasian populations. Genes and Immunity. Vol.6: 140-144

  6. Hoppa R.D., Allingham L., Brownlee K., Larcombe L. and Monks G. - 2005 An Analysis of Two Archaic Burials from Manitoba: The Eriksdale Site (EfLI-1). Canadian Journal of Archaeology Vol. 29: 234–266

  7. Nickerson, P., I Dembinski, L. Larcombe, A. Jamal, C. Rigatto, P. Orr - 2001 Cytokine Genotypes of North American Aboriginals with End-stage Renal Disease. Human Immunology . Abstracts. 27th Annual Meeting for the American Society for Histocompatability and Immunogenetics. Vol. 62, Supplement 1, pp. S62