Research Interests: Molecular characterization of hepatitis B virus (HBV): investigation of HBV genotypes, drug-resistant and immune-escape mutants; investigation of occult HBV; HBV molecular evolution; molecular epidemiology of HBV in indigenous populations of the circumpolar Arctic .
Recent Publications:
- Minuk, G.Y., Kowalec, K., Cauette, S., Larke, B., Osiowy,C. (2012) The prevalence and long term outcome of occult hepatitis B virus infections in community based populations. Journal of Medical Virology 84(9):1369-1375.
- Hong, A., Han, D., Wright, C., Burch, T., Piper, J. Osiwoy, C., Gao, C., Chiang, S., Magill, T., Dick, K., Booth, T., and Li, X. (2012). The interaction between hepatitis B virus X protein and AIB1 oncogene is required for the activation of NK kB signal transduction. Biochemical and Biophysical Research Communications 423(1):612.
- Stanojevic, B., Osiowy, C., Schaefer, S.,Bojović, K., Blogojević, J., Nešić, M., Yamashita, S., and Stamenkovic, G. (2011) Molecular characterization and phylogenetic analysis of full-genome HBV subgenotype D3 sequences from Serbia. Infection, Genetics and Evolution 11:1475-1480.
- Singh, A., Plitt, S., Osiowy, C., Surynicz, K., Kouajdo, E., Preiksaitis, J., and Lee, B. (2011) Factors Associated with Vaccine Failure and Vertical Transmission of Hepatitis B among a Cohort of Canadian Mothers and Infants. Journal of Viral Hepatitis 18(7):468-473.
- Cotelesage, J., Osiowy, C., Lawrence, C., deVarennes, S., Teow, S., Beniac, D., and Booth, T. (2011) Hepatitis B virus genotype G forms core-like particles with unique structural properties. Journal of Viral Hepatitis, 18:443-448.
- Osiowy, C., Larke, B., and Giles, E. (2011)Distinct geographic and demographic distribution of Hepatitis B virus genotypes in the Canadian Arctic as revealed through an extensive molecular epidemiological survey. Journal of Viral Hepatitis 18 (4): e11-e19..
- Osiowy, C., Kaita, K., Solar, K., and Mendoza, K. (2010) Hepatitis B virus molecular characterization and 9-year clinical profile in a patient infected with genotype I. Journal of Medical Virology 82:942-948.
Laboratory Members:
| Ms. Elizabeth Giles |
Research Technician |
(204) 789-6033 |
| Mr. Chris Huynh |
Graduate Student (MSc) |
(204) 789-8070 |
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