Dr. Carla Osiowy
Adjunct Professor
Department of Medical Microbiology, University of Manitoba
Department of Internal Medicine, Section of Hepatology, University of Manitoba
Degrees: Ph.D. (Univ. of Calgary, 1996), M.Sc. (Univ. of Manitoba, 1990)

Address:
Canadian Science Centre for Human and Animal Health (CSCHAH)
1015 Arlington Street
Winnipeg, MB, R3M 3R2

Ph: (204)-789-6061
Fax: 04)-789-2082

email: carla_osiowy@phac-aspc.gc.ca

Research Interests:
Molecular characterization of hepatitis B virus (HBV): investigation of HBV genotypes, drug-resistant and immune-escape mutants; investigation of occult HBV; HBV molecular evolution; molecular epidemiology of HBV in indigenous populations of the circumpolar Arctic .

Recent Publications:

  1. Minuk, G.Y., Kowalec, K., Cauette, S., Larke, B., Osiowy,C. (2012) The prevalence and long term outcome of occult hepatitis B virus infections in community based populations.  Journal of Medical Virology 84(9):1369-1375.
  2. Hong, A., Han, D., Wright, C., Burch, T., Piper, J. Osiwoy, C., Gao, C., Chiang, S., Magill, T., Dick, K., Booth, T., and Li, X. (2012).  The interaction between hepatitis B virus X protein and AIB1 oncogene is required for the activation of NK kB signal transduction.  Biochemical and Biophysical Research Communications 423(1):612.
  3. Stanojevic, B., Osiowy, C., Schaefer, S.,Bojović, K., Blogojević, J., Nešić, M., Yamashita, S., and Stamenkovic, G. (2011) Molecular characterization and phylogenetic analysis of full-genome HBV subgenotype D3 sequences from Serbia. Infection, Genetics and Evolution 11:1475-1480.
  4. Singh, A., Plitt, S., Osiowy, C., Surynicz, K., Kouajdo, E., Preiksaitis, J., and Lee, B. (2011) Factors Associated with Vaccine Failure and Vertical Transmission of Hepatitis B among a Cohort of Canadian Mothers and Infants. Journal of Viral Hepatitis 18(7):468-473.
  5. Cotelesage, J., Osiowy, C., Lawrence, C., deVarennes, S., Teow, S., Beniac, D., and Booth, T. (2011) Hepatitis B virus genotype G forms core-like particles with unique structural properties. Journal of Viral Hepatitis, 18:443-448.
  6. Osiowy, C., Larke, B., and Giles, E. (2011)Distinct geographic and demographic distribution of Hepatitis B virus genotypes in the Canadian Arctic as revealed through an extensive molecular epidemiological survey. Journal of Viral Hepatitis 18 (4): e11-e19..
  7. Osiowy, C., Kaita, K., Solar, K., and Mendoza, K. (2010) Hepatitis B virus molecular characterization and 9-year clinical profile in a patient infected with genotype I. Journal of Medical Virology 82:942-948.

Laboratory Members:
Ms. Elizabeth Giles Research Technician
(204) 789-6033
Mr. Chris Huynh  Graduate Student (MSc)
(204) 789-8070