Dr. Steven Mink
Recent Publications

Jacobs H, Mink SN, Duke K, Bose D, Cheng ZQ, Howlett S, Ferrier G, Light RB.  Characterization of surface membrane N-glycan binding sites of lysozyme for myocardial depression in sepsis.  Intensive Care Medicine 2005; 31:129-137.

Mink SN, Bose R, Roberts DE, Jacobs H, Duke K, Bose D, Cheng ZQ, Light RB.   Lysozyme binding to endocardial endothelium mediates myocardial depression by the nitric-oxide guanosine 3’,5’ monophosphate pathway in sepsis.  J Mol Cell Cardiol 2005; 39: 615-625.  

Buduhan G, Tan, Kasian K, Mink SN.  Volume reduction surgery impairs immediate post-operative pulmonary function in canine emphysema.  Am J Respir Crit Care Med 174:1310-1318, 2006.

Mink SN, Kasian K, Jacobs J, Cheng ZQ,  Light RB.  N,N’ – diacetylchitobiose, an inhibitor of lysozyme, reverses myocardial depression and lessens norepinephrine requirements in Escherichia coli sepsis in dogs.  Shock 29: 681-687, 2008 ( 2007 Sep 20; [Epub ahead of print]

Mink SN, Zhao-Qin Cheng, Bose R, Jacobs H, Kasian K, Roberts DE, Light RB.  Lysozyme, a mediator of sepsis, impairs cardiac adrenergic response by non-endothelial release of nitric oxide and inhibitory G protein signaling.  Am J Physiol  Heart Circ Physiol 293: 3140-3149, 2007.

Mink SN, Kasian, K, Santos-Martinez LE, Bose R, Cheng ZQ, Jacobs H, Bose R, Jacobs J, Light RB.   Lysozyme, a mediator of sepsis that produces vasodilation by hydrogen peroxide signaling in an arterial preparation.  Am J Physiol  Heart and Circ Physiol  294: H1724-H1735, 2008 [2008 Feb 8; [Epub ahead of print].

Mink SN, Jacobs H, Cheng ZQ, Kasian K, Santos-Martinez LE, Light RB.   Lysozyme, a mediator of sepsis that intrinsically generates hydrogen peroxide to cause cardiovascular collapse.  Am J Physiol  Heart and Circ Physiol  297: H930-H938, 2009 [2009 Jun 19. pub ahead of print]