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Ciprofloxacin, better known as cipro, has been in the news lately
because it is particularly effective against Anthrax. In general,
ciprofloxacin is effective against many aerobic (oxygen-requiring
or oxygen-tolerant) bacteria, but is not very useful against anaerobic
(able or required to live without oxygen) bacteria. It is a member
of the fluoroquinolone family of antibiotics. Fluoroquinolones
are derivatives of the bicyclic nitrogen heterocycle quinoline,
C9H8N. They work by interfering with the biosynthesis
of DNA and RNA, specifically by interfering with the enzyme topoisomerase.
For a very nice illustration of how ciprofloxacin and other fluoroquinolone
antibiotics work, visit http://www.bayerindia.com/baycip/bcpmode.htm.
You can find out more about ciprofloxacin from http://www.rxlist.com/cgi/generic/cipro.htm.
Please note that we are not making any medical recommendation
or endorsement by referring you to these web sites. These links are
intended only to provide interesting background material for chemistry
students about this drug compound.
Dept. Chemistry, Univ. Manitoba