Dr. George Zhanel

Dr. George G. Zhanel
Professor, Departmental of Medical Microbiology/Infectious Diseases, University of Manitoba (first appointed Assistant Professor in 1987)
Director, Canadian Antimicrobial Resistance Alliance
(CARA, http://www.can-r.ca/)

Degrees: Ph.D. Medical Microbiology (Manitoba, 1994), Doctor of Pharmacy (Minnesota, 1986)

Mailing Address: MS673- Microbiology, Health Sciences Centre
820 Sherbrook street
Winnipeg, Manitoba
Canada R3A 1R9

Tel: (204) 787-4902 Fax: (204) 787-4699
E-mail: ggzhanel@pcs.mb.ca

Research Interests:
Antibiotic resistant infections including prevalence/epidemiology, cellular and molecular resistance mechanisms, rapid diagnostics, treatment and prevention. Discovery/development of agents/methods used to prevent and/or treat infectious diseases.  

For a list of Dr. Zhanel's PubMed articles, please click here

Recent Publications: (selected from ~1000) 

1. Karlowsky JA, Adam HJ, Kosowan T, Golding GR, Nichol KA, Baxter M, Laing NM, Hoban DJ the Canadian Antimicrobial Resistance Alliance (CARA) and Zhanel GG.  PCR ribotyping and antimicrobial susceptibility testing of isolates of Clostridium difficile cultured from toxin-positive diarrheal stools of patients receiving medical care in Canadian hospitals: The Canadian Clostridium difficile surveillance study (CAN-DIFF) 2013-2015. Diagnostic Microbiology and Infectious Diseases 2018;91(2):105-111.
2. Zhanel GG, Lawrence CK, Adam H, Schweizer F, Zelenitsky S, Zhanel MA, Lagace-Wiens PR, Walkty A, Golden A, Gin AS, Hoban DJ, Lynch JP, and Karlowsky JA. Imipenem-relebactam and meropenem-vaborbactam: Two novel carbapenem--Lactamase inhibitor combinations. Drugs 2018;78(1):65-98. 
3. Domalaon R, Idowu T, Zhanel GG, Schweizer F. Antibiotic hybrids: The next generation of agents and adjuvants against Gram-negative pathogens. Clinical Microbiology reviews 2018:31(2):1-77.
4. Golden AR, Adam HJ, Karlowsky JA, Baxter MR, Nichol KA, Martin I, Demczuk W, Van Caeseele P, Gubbay JB, Lefebvre B, Horsman G, Zahariadis G, Haldane D, Gad R, German G, Mulvey MR, Gilmour MW, Hoban DJ, Zhanel GG and the Canadian Antimicrobial Resistance Alliance (CARA). Molecular characterization of predominant Streptococcus pneumoniae serotypes causing invasive infections in Canada: The SAVE study, 2011-2015. Journal of Antimicrobial Chemotherapy 2018;73(Suppl 7):20-31.  
5. Lynch JP, Zhanel GG and Clark NM. Emergence of antimicrobial resistance among Pseudomonas
 aeruginosa: Implications for therapy. Seminars in Respiratory and Critical Care Medicine 2017;38(3):326-34.5.  
6. Zhanel GG, Parkinson K, Higgins S, Denisuik A, Adam H, Pitout J, Noreddin A and Karlowsky JA.
Pharmacodynamic activity of fosfomycin versus MDR genotypically characterized and/or carbapenamse-
producing Escherichia coli using an in vitro model. Diagnostic Microbiology and Infectious Diseases 2017;
April 23.  
7. Del Rosso JQ, Webster GY, Rosen T, Thiboutot D, Leyden JJ, Gallo R, Walker C, Zhanel GG,
Eichenfield L. Status report from the scientific panel on antibiotic use in dermatology of the American
Acne and Rosacea society. Part 1: Antibiotic prescribing patterns, sources of antibiotic exposure,
antibiotic consumption, and emergence of antibiotic resistance, impact of alterations in antibiotic
prescribing and clinical sequelae of antibiotic use. The Journal of Clinical and Aesthetic Dermatology;

Patents nts:
Ten patents on novel agents with antimicrobial activity.

Teaching Interests:
Prevention and treatment of infectious diseases. 30 years teaching experience to specialists, general practitioners and students in medicine, nursing, pharmacy, biomedical sciences and lab technology. Over 50 teaching awards/nominations and a member of the Who’s Who in Medical Sciences Education (WWMSE).

Presented over 1000 lectures as an invited speaker at international, national, and local meetings speaking on the topics of prevention and treatment of infectious diseases in Canada, United States, Central America, Western and Eastern Europe including Russia, Australia, Southern and Northern Africa, the Middle East and Asia.

Consulting Interests:
Discovery and development of agents used to prevent and/or treat infectious diseases including antibiotics, antifungals, antivirals, antiparasitics, antituberculers, antiseptics, preservatives, disinfectants, sterilizers, agents with antimicrobial activity and vaccines.

 Research Colleagues:

Dr. Heather Adam Researcher (204) 787-8678