Dr. R.R. (Ron) MARQUARDT

Ph.D. (Washington State University)

Professor Emeritus

878 Kilkenny Drive
Winnipeg, Manitoba R3T 4G3 CANADA

Telephone: (204) 269-1379
Facsimile: (204) 474 7628
Email: ronald.r.marquardt@gmail.com


 
Please see a longer University of Manitoba version of my curriculum vitae for more information on myself and my research.


EDUCATION:

Name of Institution

Location

Degree

Date

Washington State University

Pullman, Wash.

Ph.D.

1965

University of Alberta

Edmonton, Alta.

M.Sc.

1961

University of Saskatchewan

Saskatoon, Sask.

B.S.A.

1958

 

POSITIONS HELD:  

1. Professor Emeritus, Department of Animal Science, University of Manitoba, Winnipeg, 2000 - present.

2. Professor, Department of Animal Science, University of Manitoba, Winnipeg - 1976 to Sept 2000.

3. Associate Professor (1970-1976) and Assistant Professor (1967-1970), Department of Animal Science, University of Manitoba, Winnipeg.

4. Postdoctoral Research Associate and Lecturer, Department of Chemistry, Washington State University, Pullman, Washington - 1965 to February 1967.

5. Research Assistant, Department of Animal Sciences (Dairy), Washington State University, Pullman, Washington - 1961 - 1965. Ph.D. research.

6. Research Assistant, Department of Animal Sciences, University of Alberta, Edmonton, Alberta. M.Sc. research. 1959-1961.

 

PUBLICATIONS:

1.       Refereed Peer Reviewed Journals (Total = 247)

2.       Proceedings (Total = 64)

3.       Books (1)

4.       Book Chapters and Invited Reviews (Total = 23)

5.       Abstracts of Scientific Presentations: (More than 50)

SELECTED PUBLICATIONS AND THEIR CITATIONS:
1. Mycotoxins; Ochratoxin A:

1.1 Marquardt, R.R. and A.A. Frohlich. 1992. A review of recent advances in understanding ochratoxicosis. J. Anim. Sci. (invited review), 70:3968-3988, Citations 338.

1.2 Li, S., R.R. Marquardt, A.A. Frohlich, T.G. Vitti and G. Crow. 1997. Pharmacokinetics of ochratoxin A and its metabolites in rats. Toxicol. Appl. Pharmacol. 145:82-90, Citations 101.

1.3 Xiao, H., M.S. Madhyastha, R.R. Marquardt, S. Li, J.K. Vodela and W. Kemppainen. 1996. Toxicity of ochratoxin A, its opened lactone and several of its analogs: structure-activity relationships. Toxicol. Appl. Pharmacol. 137:182-192, Citations 95.

1.4 Hoehler, D. and R.R. Marquardt. 1996. Influence of vitamins E and C on the toxic effects of ochratoxin A and T-2 toxin in chicks. Poultry Sci. 75:1508-1515, Citations 82.

2. Control of Intestinal Pathogens:

2.1 Marquardt, R.R., L.Z. Jin, J-W. Kim, L. Fang, A.A. Frohlich and S.K. Baidoo. 1999. Passive protective effect of egg-yolk antibodies against enterotoxigenic Escherichia coli K88+ infection in neonatal and early weaned piglets. FEBS Immunol. Med. Microbiol.23:283-288, Citations 184.

2.2 Owusu-Asiedu, A., C.M. Nyachoti, and R.R. Marquardt. 2003. Response of early-weaned pigs to an enterotoxigenic Escherichia coli (K88) challenge when fed diets containing spray-dried porcine or pea protein isolate plus egg-yolk antibody, zinc oxide, furmaric acid or antibiotic. J. Animal Sci. 81:1790-1798, Citations 134.

2.3 Jin, L.Z., R.R. Marquardt and X. Zhao. 2000. A Strain of Enterococcus faecium (18C23) inhibits adhesion of enterotoxigenic Escherichia coli K88 to porcine small intestine mucus. Appl. Environ. Microbiol. 66:4100-4204, Citations 110.

2.4 Jin, L.Z., S.K. Baidoo, R.R. Marquardt and A.A. Frohlich. 1998. In vitro inhibition of adhesion of enterotoxigenic Escherichia coli K88 to piglet mucus by egg-yolk antibodies. FEBS Immunol. Med. Microb. 21:313-321, Citations 94.

3. Enzymes for Enhanced Nutrient Digestibility:

3.1 Brenes, A., M. Smith, W. Guenter and R.R. Marquardt. 1993. Effect of enzyme supplementation on the performance and digestive tract size of broiler chickens fed wheat and barley-based diets. Poultry Sci. 72:1731-1739, Citations 195.

3.2 Friesen, O.D., W. Guenter, R.R. Marquardt and B.A. Rotter. 1992. The effect of enzyme supplementation on the apparent metabolizable energy and nutrient digestibilities of wheat, barley, oats and rye for the young broiler chick. Poultry Sci. 71:1710-1721, Citations 172.

3.3 Marquardt, R.R., D. Boros, W. Guenter and G. Crow. 1994. The nutritive value of barley, rye, wheat and corn for chicks as affected by the use of Trichoderma reesei enzyme preparation. Anim. Feed Sci. Tech. 45:363-378, Citations 106.

3.4 Brenes, A., R.R. Marquardt, W. Guenter and B.A. Rotter. 1993. Effect of enzyme supplementation on the nutritional value of raw, autoclaved and dehulled lupins (Lupinus albus) in chicken diets. Poultry Sci. 72:2281-2293, Citations 86.

4. Identification of Anti-Nutritional Factors (Arabinoxylans; Pentosans) In Rye Grain:

4.1 Fengler, A.I. and R.R. Marquardt. 1988. Antinutritive properties of the water-soluble pentosans from rye: II. Effects on rate of dialysis of nutrients in vitro and the retention of nutrients by the chick. Cereal Chem. 65:298-302, Citations 156.

4.2 Antoniou, T., R.R. Marquardt and P.E. Cansfield. 1981. Isolation, partial characterization and antinutritional activity of a factor (pentosans) in rye grain. J. Agric. Food Chem. 29:1240-1247, Citations 114. 

 
AWARDS:
 

1. Canadian Society of Animal Science Award of Merit. 1998. This is the highest award of the Society.

2. Jiangsu Province Friendship Award for excellence in cooperative work between Nanjing Agricultural University, China, and University of Manitoba, (December 1997).

3. Shur-gain Award for Excellence in Nutrition and Meat Sciences. This is the highest award that the Canadian Society of Animal Science bestows in the field of Nutrition and Meat Science. (July 1992).

4. Sigma Xi (Manitoba Chapter) Senior Scientist Award. Awarded annually to an individual who has made an outstanding contribution in the field of science in Manitoba, April 1992.

5. University of Manitoba Graduate Students Association Award for Excellence in Graduate Teaching, 1990-1991. Nominations are made by the Graduate Students.

6. Faculty of Agriculture Merit Award

7. Appointed Professor in May 1994 in the Laboratory of Animal Physiology and Biochemistry, Nanjing Agricultural University, Nanjing P.R. China. This laboratory was designated as one of the key National Laboratories in China.

 

TEACHING:

1. Principles of Nutritional Toxicology

2. Advanced Animal Metabolism

3. Protein Metabolism

 

VISITING SCIENTISTS, RESEARCH ASSOCIATES AND GRADUATE STUDENTS:

1. Research Associates and Visiting Scientists: China (9), Spain (7), Canada (5), Korea (3), Poland (3), India (2), Egypt (2), Germany (1), Israel (1); Total 33.

2. Ph.D. Students: Total Ph.D. Students: 14

3. M.Sc. Students: Total M.Sc. Students: 12

 

MEMBERSHIP IN ORGANIZATIONS, SOCIETIES, ETC.:

           
Ten societies

 

UNIVERSITY COMMITTEES AND ADMINISTRATIVE SERVICES (1985 - 2000):


Thirteen committees

 

NATIONAL AND INTERNATIONAL COMMITTEES (1985 - current): 

1. Expert Evaluator for Food Quality and Safety, Integrated Food Chain Panel, European Commission, Brussels (June and July 2000)

2. Member, IRTAS (Institut de Recerca & Tecnologia Agroalimentaries), Scientific Advisory Committee, Barcelona, Spain (2001–2004)

3. Member, Committee on Animal Nutrition, National Research Council, National Academy of Sciences (US) (1990-1993) (Canadian Delegate)
4. Editor, Canadian Journal of Animal Science (1990-1993)
5. Member, Scientific Journals Committee; Agricultural Institute of Canada (1990-1993)
6. Member of Editorial Policy Board, Canadian Journals of Agricultural Sciences (1989-1993)

7. Member of NSERC (National Science and Engineering Council of Canada) Strategic Grants Selection Panel on Food, Agriculture and Aquaculture (1991-1992)
8. Member of NSERC Grant Selection Committee for Animal Biology, (1985-1988)
9. Member of International Union of Nutritional Sciences Executive Committee (1985-1993)
10. Associate Editor Canadian Journal of Animal Science (1988-91)

 

COMPANIES FOUNDED:

  1. One of two founders (Oct 2005) and President of All Natural Nutritional Products (ANNP) Inc.
  2. One of three founders (November 2001) and Vice President of Research and Development of Zyme Fast, Inc.
  3. One of four founders of Norzyme Inc. (February 2000). Its mission was to develop and market low cost highly efficient kits using patented technology to detect a wide range of protease molecules and protease inhibiters
  4. One of two founders of NutraTech Inc. (July 1999). Its mission was to produce therapeutical antibodies in the egg of laying hans to control intestinal diseases 

ACTIVITY SINCE RETIREMENT IN 2000:

1.     Zyme Fast - Antibodies as an Alternative to Antibiotics: 

Zyme Fast, Inc. was incorporated by T. Sellen, L. Fang and R.R. Marquardt. Its mission is to produce therapeutic antibodies for the control and mitigation of intestinal pathogens in animals and humans using antibodies from laying hens hyperimmunized against recombinant expressed virulence factors (specific antigens). The procedure has been shown to be hightly effective at controlling several intestinal pathogens including Clostridium difficile (the hospital pathogen); enterotoxigenic E.coli, and rotovirus in pigs, and pig epidemic diarrhea virus (PEDV) which has recently caused large economic losses in North America. Zyme Fast has also developed proprietory methods for the recombinant production of high concentrations of peptides such as epidermal growth factor (EGF). EGF has been shown to be high effective as a growth promotant in pigs.

2.      All Natural Nutritional Products (ANNP) Inc.:

ANNP's principals are Dr. S. Li and R.R. Marquardt. ANNP's mission is to develop and market nutraceutical supplements that will enhance health and well-being in humans. Currently it has been issued Natural Products Numbers (NPNs) from Health Canada for eight of its products. Several research projects have been funded by NSERC and IRAP (National Research Council).

3.      Research Conducted by R.R. Marquardt since Retirement In 2000:

R.R. Marquardt has published 27 peer-reviewed papers, continued to supervise two Ph.D. students, and served as an Advisor for several Ph.D. candidates. In addition, he has been instrumental in obtaining more than five National grants for research on:

3.1 Production of therapeutic antibodies against intestinal diseases in animals;

3.2 Evaluation of efficacy of EGF in the control of mastitis in lactating cows;

3.3 The development of lateral flow immunologist assays for the detection of Salmonella enteritidis and F4 E.coli;

3.4 The development of a High Performance Liquid Chromatographical (HPLC) method for the simultaneous analyses of resveratrol, quercetin, and emodin in nutraceutical supplements and;

3.5 The identification and isolation of bioactive compounds in Red-Osier dogwood, a unique and highly beneficial native plant.

 

 COMMUNITY SERVICE:

1.         Coach of Fort Richmond Community Club Hockey Team

2.         Coach of Fort Richmond Community Club Soccer Team

3.         Coordinator of Aggie Row Curling Club

4.         Coach of Fort Richmond Community Club Ringette Team 

5.         Assistant Coach and Treasurer of Manitoba Marlin's Swim Club 

 

DETAILED CV INFORMATION:

Detailed information for Dr. R. R. Marquardt's Curriculum Vitae can be obtained from the Department of Animal Science, the University of Manitoba website at

 http://www.umanitoba.ca/afs/animal_science/staff/academic/marquardtpage.html