Dr. Ryan Zarychanski is a professor of medicine at the University of Manitoba (hematology & critical care) internationally recognized clinical trialist and research leader. He holds a Tier 1 Canada Research Chair in Clinical
Trials and serves as scientific director of both Aurora Clinical Research and the George & Fay Yee Centre for Healthcare Innovation, Manitoba’s SPOR/SUPPORT unit.
His research focuses on hematologic aspects of critical illness where he leads trials in the fields of sepsis, anticoagulation, and blood conservation while advancing innovative clinical trial methods to integrate clinical trials into routine healthcare delivery.
Building on ward-based research infrastructure Dr. Zarychanski developed in COVID-19 pandemic, he currently serves as Chair of GUARD_Resp, an international platform trial that evaluates therapies to improve outcomes for patients with pneumonia. Dr. Zarychanski led the TRACTION trial, a landmark policy randomized trial that demonstrated the ability of tranexamic to safely reduce blood transfusion in patients having major non-cardiac surgical procedures.
Dr. Zarychanski has secured more than $100 million in research funding as a primary investigator, published over 250 peer-reviewed articles, and built research infrastructure that supports investigators across Manitoba, Canada, and internationally.
Education
Master of Science in Epidemiology, University of Ottawa (2010)
Clinical Investigator Program, University of Ottawa (2008)
Critical Care Fellowship, University of Manitoba (2006)
Haematology Fellowship, University of Manitoba/CancerCare Manitoba (2005)
Internal Medicine Residency, University of Manitoba (2003)
Doctor of Medicine, University of Ottawa (2000)
Bachelor of Science in Medicine, University of Manitoba (1995)
Bachelor of Science, University of Manitoba (1995)
Awards
2025:
- Tier 1 Canada Research Chair in Clinical Trials, University of Manitoba
2024:
- Fellow, Canadian Academy of Health Sciences (FCAHS)
2023:
- Physician of the Year, Doctors Manitoba
2021:
- Excellence in Research and Mentorship Award, Department of Medical Oncology and Hematology, CancerCare Manitoba
- Canadian Hematology Paper of the Year, Canadian Hematology Society
2020:
- Lyonel G. Israels Research Chair in Hematology
2019:
- Mentor of the Year Award, Royal College of Physicians and Surgeons of Canada
2017:
- Excellence in Research and Mentorship Award, CancerCare Manitoba
- Doctors Manitoba Scholastic Award
2016:
- Lyonel G. Israels Professorship in Hematology, University of Manitoba
2015:
- CFPC Continuing Professional Development (CPD) Award, College of Family Physicians of Canada
- Joe Doupe Memorial Lecture, University of Manitoba